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Molecular insights of hyaluronic acid-hydroxychloroquine conjugate as a promising drug in targeting SARS-CoV-2 viral proteins

In-silico anti-viral activity of Hydroxychloroquine (HCQ) and its Hyaluronic Acid-derivative (HA-HCQ) towards different SARS-CoV-2 protein molecular targets were studied. Four different SARS-CoV-2 proteins molecular target i.e., three different main proteases and one helicase were chosen for In-sili...

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Detalles Bibliográficos
Autores principales: Thirumalaisamy, R., Aroulmoji, V., Iqbal, Muhammad Nasir, Deepa, M., Sivasankar, C., Khan, Riaz, Selvankumar, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041731/
https://www.ncbi.nlm.nih.gov/pubmed/33867575
http://dx.doi.org/10.1016/j.molstruc.2021.130457