Structural basis for an exceptionally strong preference for asparagine residue at the S2 subsite of Stenotrophomonas maltophilia dipeptidyl peptidase 7

The emergence of drug-resistant bacteria has become a major problem worldwide. Bacterial dipeptidyl peptidases 7 and 11 (DPP7s and DPP11s), belonging to the family-S46 peptidases, are important enzymes for bacterial growth and are not present in mammals. Therefore, specific inhibitors for these pept...

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Detalles Bibliográficos
Autores principales: Nakamura, Akihiro, Suzuki, Yoshiyuki, Sakamoto, Yasumitsu, Roppongi, Saori, Kushibiki, Chisato, Yonezawa, Natsuri, Takahashi, Masato, Shida, Yosuke, Gouda, Hiroaki, Nonaka, Takamasa, Tanaka, Nobutada, Ogasawara, Wataru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041751/
https://www.ncbi.nlm.nih.gov/pubmed/33846449
http://dx.doi.org/10.1038/s41598-021-86965-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041751/
https://www.ncbi.nlm.nih.gov/pubmed/33846449
http://dx.doi.org/10.1038/s41598-021-86965-x

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