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The transcription factor Sox7 modulates endocardiac cushion formation contributed to atrioventricular septal defect through Wnt4/Bmp2 signaling

Cardiac septum malformations account for the largest proportion in congenital heart defects. The transcription factor Sox7 has critical functions in the vascular development and angiogenesis. It is unclear whether Sox7 also contributes to cardiac septation development. We identified a de novo 8p23.1...

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Detalles Bibliográficos
Autores principales: Hong, Nanchao, Zhang, Erge, Xie, Huilin, Jin, Lihui, Zhang, Qi, Lu, Yanan, Chen, Alex F., Yu, Yongguo, Zhou, Bin, Chen, Sun, Yu, Yu, Sun, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041771/
https://www.ncbi.nlm.nih.gov/pubmed/33846290
http://dx.doi.org/10.1038/s41419-021-03658-z