Endoplasmic reticulum acetyltransferases Atase1 and Atase2 differentially regulate reticulophagy, macroautophagy and cellular acetyl-CoA metabolism

N(ε)-lysine acetylation in the ER lumen is a recently discovered quality control mechanism that ensures proteostasis within the secretory pathway. The acetyltransferase reaction is carried out by two type-II membrane proteins, ATase1/NAT8B and ATase2/NAT8. Prior studies have shown that reducing ER a...

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Detalles Bibliográficos
Autores principales: Rigby, Michael J., Lawton, Alexis J., Kaur, Gulpreet, Banduseela, Varuna C., Kamm, William E., Lakkaraju, Aparna, Denu, John M., Puglielli, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041774/
https://www.ncbi.nlm.nih.gov/pubmed/33846551
http://dx.doi.org/10.1038/s42003-021-01992-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041774/
https://www.ncbi.nlm.nih.gov/pubmed/33846551
http://dx.doi.org/10.1038/s42003-021-01992-8

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