Cargando…

CDC2-like (CLK) protein kinase inhibition as a novel targeted therapeutic strategy in prostate cancer

Dysregulation of alternative splicing is a feature of cancer, both in aetiology and progression. It occurs because of mutations in splice sites or sites that regulate splicing, or because of the altered expression and activity of splice factors and of splice factor kinases that regulate splice facto...

Descripción completa

Detalles Bibliográficos
Autores principales: Uzor, Simon, Porazinski, Sean R., Li, Ling, Clark, Bethany, Ajiro, Masahiko, Iida, Kei, Hagiwara, Masatoshi, Alqasem, Abdullah A., Perks, Claire M., Wilson, Ian D., Oltean, Sebastian, Ladomery, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041776/
https://www.ncbi.nlm.nih.gov/pubmed/33846420
http://dx.doi.org/10.1038/s41598-021-86908-6