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CDC2-like (CLK) protein kinase inhibition as a novel targeted therapeutic strategy in prostate cancer
Dysregulation of alternative splicing is a feature of cancer, both in aetiology and progression. It occurs because of mutations in splice sites or sites that regulate splicing, or because of the altered expression and activity of splice factors and of splice factor kinases that regulate splice facto...
Autores principales: | Uzor, Simon, Porazinski, Sean R., Li, Ling, Clark, Bethany, Ajiro, Masahiko, Iida, Kei, Hagiwara, Masatoshi, Alqasem, Abdullah A., Perks, Claire M., Wilson, Ian D., Oltean, Sebastian, Ladomery, Michael R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041776/ https://www.ncbi.nlm.nih.gov/pubmed/33846420 http://dx.doi.org/10.1038/s41598-021-86908-6 |
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