Staphylococcus aureus vWF-binding protein triggers a strong interaction between clumping factor A and host vWF

The Staphylococcus aureus cell wall-anchored adhesin ClfA binds to the very large blood circulating protein, von Willebrand factor (vWF) via vWF-binding protein (vWbp), a secreted protein that does not bind the cell wall covalently. Here we perform force spectroscopy studies on living bacteria to un...

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Detalles Bibliográficos
Autores principales: Viljoen, Albertus, Viela, Felipe, Mathelié-Guinlet, Marion, Missiakas, Dominique, Pietrocola, Giampiero, Speziale, Pietro, Dufrêne, Yves F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041789/
https://www.ncbi.nlm.nih.gov/pubmed/33846500
http://dx.doi.org/10.1038/s42003-021-01986-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041789/
https://www.ncbi.nlm.nih.gov/pubmed/33846500
http://dx.doi.org/10.1038/s42003-021-01986-6

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