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Reovirus directly engages integrin to recruit clathrin for entry into host cells

Reovirus infection requires the concerted action of viral and host factors to promote cell entry. After interaction of reovirus attachment protein σ1 with cell-surface carbohydrates and proteinaceous receptors, additional host factors mediate virus internalization. In particular, β1 integrin is requ...

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Detalles Bibliográficos
Autores principales: Koehler, Melanie, Petitjean, Simon J. L., Yang, Jinsung, Aravamudhan, Pavithra, Somoulay, Xayathed, Lo Giudice, Cristina, Poncin, Mégane A., Dumitru, Andra C., Dermody, Terence S., Alsteens, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041799/
https://www.ncbi.nlm.nih.gov/pubmed/33846319
http://dx.doi.org/10.1038/s41467-021-22380-0