Reciprocal regulation of RIG-I and XRCC4 connects DNA repair with RIG-I immune signaling

The RNA-sensing pathway contributes to type I interferon (IFN) production induced by DNA damaging agents. However, the potential involvement of RNA sensors in DNA repair is unknown. Here, we found that retinoic acid-inducible gene I (RIG-I), a key cytosolic RNA sensor that recognizes RNA virus and i...

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Detalles Bibliográficos
Autores principales: Guo, Guijie, Gao, Ming, Gao, Xiaochen, Zhu, Bibo, Huang, Jinzhou, Tu, Xinyi, Kim, Wootae, Zhao, Fei, Zhou, Qin, Zhu, Shouhai, Wu, Zheming, Yan, Yuanliang, Zhang, Yong, Zeng, Xiangyu, Zhu, Qian, Yin, Ping, Luo, Kuntian, Sun, Jie, Deng, Min, Lou, Zhenkun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041803/
https://www.ncbi.nlm.nih.gov/pubmed/33846346
http://dx.doi.org/10.1038/s41467-021-22484-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041803/
https://www.ncbi.nlm.nih.gov/pubmed/33846346
http://dx.doi.org/10.1038/s41467-021-22484-7

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