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Reciprocal regulation of RIG-I and XRCC4 connects DNA repair with RIG-I immune signaling
The RNA-sensing pathway contributes to type I interferon (IFN) production induced by DNA damaging agents. However, the potential involvement of RNA sensors in DNA repair is unknown. Here, we found that retinoic acid-inducible gene I (RIG-I), a key cytosolic RNA sensor that recognizes RNA virus and i...
Autores principales: | Guo, Guijie, Gao, Ming, Gao, Xiaochen, Zhu, Bibo, Huang, Jinzhou, Tu, Xinyi, Kim, Wootae, Zhao, Fei, Zhou, Qin, Zhu, Shouhai, Wu, Zheming, Yan, Yuanliang, Zhang, Yong, Zeng, Xiangyu, Zhu, Qian, Yin, Ping, Luo, Kuntian, Sun, Jie, Deng, Min, Lou, Zhenkun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041803/ https://www.ncbi.nlm.nih.gov/pubmed/33846346 http://dx.doi.org/10.1038/s41467-021-22484-7 |
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