Coevolution underlies GPCR-G protein selectivity and functionality

G protein-coupled receptors (GPCRs) regulate diverse physiological events, which makes them as the major targets for many approved drugs. G proteins are downstream molecules that receive signals from GPCRs and trigger cell responses. The GPCR-G protein selectivity mechanism on how they properly and...

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Detalles Bibliográficos
Autores principales: Seo, Min Jae, Heo, Joongyu, Kim, Kyunghui, Chung, Ka Young, Yu, Wookyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041822/
https://www.ncbi.nlm.nih.gov/pubmed/33846507
http://dx.doi.org/10.1038/s41598-021-87251-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041822/
https://www.ncbi.nlm.nih.gov/pubmed/33846507
http://dx.doi.org/10.1038/s41598-021-87251-6

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