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The long noncoding RNA of RMRP is downregulated by PERK, which induces apoptosis in hepatocellular carcinoma cells

Endoplasmic reticulum (ER) stress plays an important role in hepatocyte degeneration, especially in patients with chronic liver injury. Protein kinase R-like endoplasmic reticulum kinase (PERK) is a key molecule in ER stress. PERK may contribute to apoptotic cell death in HCC, however the details of...

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Detalles Bibliográficos
Autores principales: Yukimoto, Atsushi, Watanabe, Takao, Sunago, Kotaro, Nakamura, Yoshiko, Tanaka, Takaaki, Koizumi, Yohei, Yoshida, Osamu, Tokumoto, Yoshio, Hirooka, Masashi, Abe, Masanori, Hiasa, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041825/
https://www.ncbi.nlm.nih.gov/pubmed/33846370
http://dx.doi.org/10.1038/s41598-021-86592-6