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Role of Hakai in m(6)A modification pathway in Drosophila

N6-methyladenosine (m(6)A), the most abundant internal modification in eukaryotic mRNA, is installed by a multi-component writer complex; however, the exact roles of each component remain poorly understood. Here we show that a potential E3 ubiquitin ligase Hakai colocalizes and interacts with other...

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Detalles Bibliográficos
Autores principales: Wang, Yanhua, Zhang, Lifeng, Ren, Hang, Ma, Lijuan, Guo, Jian, Mao, Decai, Lu, Zhongwen, Lu, Lijun, Yan, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041851/
https://www.ncbi.nlm.nih.gov/pubmed/33846330
http://dx.doi.org/10.1038/s41467-021-22424-5