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An acute phase protein α(1)-acid glycoprotein mitigates AKI and its progression to CKD through its anti-inflammatory action

The molecular mechanism for acute kidney injury (AKI) and its progression to chronic kidney disease (CKD) continues to be unclear. In this study, we investigated the pathophysiological role of the acute phase protein α(1)-acid glycoprotein (AGP) in AKI and its progression to CKD using AGP KO mice. P...

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Detalles Bibliográficos
Autores principales: Watanabe, Hiroshi, Fujimura, Rui, Hiramoto, Yuto, Murata, Ryota, Nishida, Kento, Bi, Jing, Imafuku, Tadashi, Komori, Hisakazu, Maeda, Hitoshi, Mukunoki, Ayumi, Takeo, Toru, Nakagata, Naomi, Tanaka, Motoko, Matsushita, Kazutaka, Fukagawa, Masafumi, Maruyama, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041882/
https://www.ncbi.nlm.nih.gov/pubmed/33846468
http://dx.doi.org/10.1038/s41598-021-87217-8