Sustained high expression of multiple APOBEC3 cytidine deaminases in systemic lupus erythematosus

APOBEC3 (A3) enzymes are best known for their role as antiviral restriction factors and as mutagens in cancer. Although four of them, A3A, A3B, A3F and A3G, are induced by type-1-interferon (IFN-I), their role in inflammatory conditions is unknown. We thus investigated the expression of A3, and part...

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Detalles Bibliográficos
Autores principales: Perez-Bercoff, Danielle, Laude, Hélène, Lemaire, Morgane, Hunewald, Oliver, Thiers, Valérie, Vignuzzi, Marco, Blanc, Hervé, Poli, Aurélie, Amoura, Zahir, Caval, Vincent, Suspène, Rodolphe, Hafezi, François, Mathian, Alexis, Vartanian, Jean-Pierre, Wain-Hobson, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041901/
https://www.ncbi.nlm.nih.gov/pubmed/33846459
http://dx.doi.org/10.1038/s41598-021-87024-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041901/
https://www.ncbi.nlm.nih.gov/pubmed/33846459
http://dx.doi.org/10.1038/s41598-021-87024-1

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