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Microvascularized tumor organoids-on-chips: advancing preclinical drug screening with pathophysiological relevance

Recent developments of organoids engineering and organ-on-a-chip microfluidic technologies have enabled the recapitulation of the major functions and architectures of microscale human tissue, including tumor pathophysiology. Nevertheless, there remain challenges in recapitulating the complexity and...

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Detalles Bibliográficos
Autores principales: Lim, Jungeun, Ching, Hanna, Yoon, Jeong-Kee, Jeon, Noo Li, Kim, YongTae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042002/
https://www.ncbi.nlm.nih.gov/pubmed/33846849
http://dx.doi.org/10.1186/s40580-021-00261-y