Therapeutic B-cell depletion reverses progression of Alzheimer’s disease

The function of B cells in Alzheimer’s disease (AD) is not fully understood. While immunoglobulins that target amyloid beta (Aβ) may interfere with plaque formation and hence progression of the disease, B cells may contribute beyond merely producing immunoglobulins. Here we show that AD is associate...

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Detalles Bibliográficos
Autores principales: Kim, Ki, Wang, Xin, Ragonnaud, Emeline, Bodogai, Monica, Illouz, Tomer, DeLuca, Marisa, McDevitt, Ross A., Gusev, Fedor, Okun, Eitan, Rogaev, Evgeny, Biragyn, Arya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042032/
https://www.ncbi.nlm.nih.gov/pubmed/33846335
http://dx.doi.org/10.1038/s41467-021-22479-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042032/
https://www.ncbi.nlm.nih.gov/pubmed/33846335
http://dx.doi.org/10.1038/s41467-021-22479-4

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