Cargando…
Therapeutic B-cell depletion reverses progression of Alzheimer’s disease
The function of B cells in Alzheimer’s disease (AD) is not fully understood. While immunoglobulins that target amyloid beta (Aβ) may interfere with plaque formation and hence progression of the disease, B cells may contribute beyond merely producing immunoglobulins. Here we show that AD is associate...
Autores principales: | Kim, Ki, Wang, Xin, Ragonnaud, Emeline, Bodogai, Monica, Illouz, Tomer, DeLuca, Marisa, McDevitt, Ross A., Gusev, Fedor, Okun, Eitan, Rogaev, Evgeny, Biragyn, Arya |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042032/ https://www.ncbi.nlm.nih.gov/pubmed/33846335 http://dx.doi.org/10.1038/s41467-021-22479-4 |
Ejemplares similares
-
Restoring microglial and astroglial homeostasis using DNA immunization in a Down Syndrome mouse model
por: Illouz, Tomer, et al.
Publicado: (2018) -
Gut microbiota as the key controllers of “healthy” aging of elderly people
por: Ragonnaud, Emeline, et al.
Publicado: (2021) -
Maternal antibodies facilitate Amyloid-β clearance by activating Fc-receptor-Syk-mediated phagocytosis
por: Illouz, Tomer, et al.
Publicado: (2021) -
Dissection of the Human T-Cell Receptor γ Gene Repertoire in the Brain and Peripheral Blood Identifies Age- and Alzheimer's Disease-Associated Clonotype Profiles
por: Aliseychik, Maria, et al.
Publicado: (2020) -
Cancer co-opts differentiation of B-cell precursors into macrophage-like cells
por: Chen, Chen, et al.
Publicado: (2022)