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Autonomous Purkinje cell activation instructs bidirectional motor learning through evoked dendritic calcium signaling
The signals in cerebellar Purkinje cells sufficient to instruct motor learning have not been systematically determined. Therefore, we applied optogenetics in mice to autonomously excite Purkinje cells and measured the effect of this activity on plasticity induction and adaptive behavior. Ex vivo, ex...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042043/ https://www.ncbi.nlm.nih.gov/pubmed/33846328 http://dx.doi.org/10.1038/s41467-021-22405-8 |