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Autonomous Purkinje cell activation instructs bidirectional motor learning through evoked dendritic calcium signaling

The signals in cerebellar Purkinje cells sufficient to instruct motor learning have not been systematically determined. Therefore, we applied optogenetics in mice to autonomously excite Purkinje cells and measured the effect of this activity on plasticity induction and adaptive behavior. Ex vivo, ex...

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Detalles Bibliográficos
Autores principales:	Bonnan, Audrey, Rowan, Matthew M. J., Baker, Christopher A., Bolton, M. McLean, Christie, Jason M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042043/ https://www.ncbi.nlm.nih.gov/pubmed/33846328 http://dx.doi.org/10.1038/s41467-021-22405-8

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