Uncovering transcriptional dark matter via gene annotation independent single-cell RNA sequencing analysis

Conventional scRNA-seq expression analyses rely on the availability of a high quality genome annotation. Yet, as we show here with scRNA-seq experiments and analyses spanning human, mouse, chicken, mole rat, lemur and sea urchin, genome annotations are often incomplete, in particular for organisms t...

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Detalles Bibliográficos
Autores principales: Wang, Michael F. Z., Mantri, Madhav, Chou, Shao-Pei, Scuderi, Gaetano J., McKellar, David W., Butcher, Jonathan T., Danko, Charles G., De Vlaminck, Iwijn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042062/
https://www.ncbi.nlm.nih.gov/pubmed/33846360
http://dx.doi.org/10.1038/s41467-021-22496-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042062/
https://www.ncbi.nlm.nih.gov/pubmed/33846360
http://dx.doi.org/10.1038/s41467-021-22496-3

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