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Uncovering transcriptional dark matter via gene annotation independent single-cell RNA sequencing analysis
Conventional scRNA-seq expression analyses rely on the availability of a high quality genome annotation. Yet, as we show here with scRNA-seq experiments and analyses spanning human, mouse, chicken, mole rat, lemur and sea urchin, genome annotations are often incomplete, in particular for organisms t...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042062/ https://www.ncbi.nlm.nih.gov/pubmed/33846360 http://dx.doi.org/10.1038/s41467-021-22496-3 |