Association of genetic variants in TPMT, ITPA, and NUDT15 with azathioprine-induced myelosuppression in southwest china patients with autoimmune hepatitis

This study aimed to investigate the influence of TPMT*3C, ITPA, NUDT15, and 6-thioguanine nucleotides (6-TGN) on azathioprine (AZA)-induced myelosuppression in Southwest China patients with autoimmune hepatitis (AIH). A total of 113 Chinese patients with AIH receiving AZA maintenance treatment were...

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Detalles Bibliográficos
Autores principales: Miao, Qiang, Yan, Lin, Zhou, Yanhong, Li, Yi, Zou, Yuangao, Wang, Lanlan, Bai, Yangjuan, Zhang, Junlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042108/
https://www.ncbi.nlm.nih.gov/pubmed/33846471
http://dx.doi.org/10.1038/s41598-021-87095-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042108/
https://www.ncbi.nlm.nih.gov/pubmed/33846471
http://dx.doi.org/10.1038/s41598-021-87095-0

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