Behavioral Consequences of a Combination of Gad1 Haplodeficiency and Adolescent Exposure to an NMDA Receptor Antagonist in Long-Evans Rats

Glutamate decarboxylase 67-kDa isoform (GAD67), which is encoded by the GAD1 gene, is one of the key enzymes that produce GABA. The reduced expression of GAD67 has been linked to the pathophysiology of schizophrenia. Additionally, the excitatory glutamatergic system plays an important role in the de...

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Detalles Bibliográficos
Autores principales: Fujihara, Kazuyuki, Sato, Takumi, Higeta, Kazuya, Miyasaka, Yoshiki, Mashimo, Tomoji, Yanagawa, Yuchio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042137/
https://www.ncbi.nlm.nih.gov/pubmed/33859565
http://dx.doi.org/10.3389/fphar.2021.646088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042137/
https://www.ncbi.nlm.nih.gov/pubmed/33859565
http://dx.doi.org/10.3389/fphar.2021.646088

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