The cell surface hyaluronidase TMEM2 regulates cell adhesion and migration via degradation of hyaluronan at focal adhesion sites

The extracellular matrix (ECM) plays an important role in maintaining tissue homeostasis and poses a significant physical barrier to in vivo cell migration. Accordingly, as a means of enhancing tissue invasion, tumor cells use matrix metalloproteinases to degrade ECM proteins. However, the in vivo E...

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Detalles Bibliográficos
Autores principales: Irie, Fumitoshi, Tobisawa, Yuki, Murao, Ayako, Yamamoto, Hayato, Ohyama, Chikara, Yamaguchi, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042168/
https://www.ncbi.nlm.nih.gov/pubmed/33647313
http://dx.doi.org/10.1016/j.jbc.2021.100481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042168/
https://www.ncbi.nlm.nih.gov/pubmed/33647313
http://dx.doi.org/10.1016/j.jbc.2021.100481

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