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Multisite NHERF1 phosphorylation controls GRK6A regulation of hormone-sensitive phosphate transport

The type II sodium-dependent phosphate cotransporter (NPT2A) mediates renal phosphate uptake. The NPT2A is regulated by parathyroid hormone (PTH) and fibroblast growth factor 23, which requires Na(+)/H(+) exchange regulatory factor-1 (NHERF1), a multidomain PDZ-containing phosphoprotein. Phosphocycl...

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Detalles Bibliográficos
Autores principales: Vistrup-Parry, Maria, Sneddon, W. Bruce, Bach, Sofie, Strømgaard, Kristian, Friedman, Peter A., Mamonova, Tatyana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042174/
https://www.ncbi.nlm.nih.gov/pubmed/33639163
http://dx.doi.org/10.1016/j.jbc.2021.100473