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Brown adipocyte-specific knockout of Bmal1 causes mild but significant thermogenesis impairment in mice
OBJECTIVE: Impaired circadian clocks can cause obesity, but their pathophysiological role in brown adipose tissue (BAT), a major tissue regulating energy metabolism, remains unclear. To address this issue, we investigated the effects of complete disruption of the BAT clock on thermogenesis and energ...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042177/ https://www.ncbi.nlm.nih.gov/pubmed/33676029 http://dx.doi.org/10.1016/j.molmet.2021.101202 |