Cargando…

IFN-I-tolerant oncolytic Semliki Forest virus in combination with anti-PD1 enhances T cell response against mouse glioma

Oncolytic virotherapy holds promise of effective immunotherapy against otherwise nonresponsive cancers such as glioblastoma. Our previous findings have shown that although oncolytic Semliki Forest virus (SFV) is effective against various mouse glioblastoma models, its therapeutic potency is hampered...

Descripción completa

Detalles Bibliográficos
Autores principales: Martikainen, Miika, Ramachandran, Mohanraj, Lugano, Roberta, Ma, Jing, Martikainen, Minttu-Maria, Dimberg, Anna, Yu, Di, Merits, Andres, Essand, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042242/
https://www.ncbi.nlm.nih.gov/pubmed/33869741
http://dx.doi.org/10.1016/j.omto.2021.03.008