Site-Specific Introduction of Negative Charges on the Protein Surface for Improving Global Functions of Recombinant Fetal Hemoglobin

Due to its compatible oxygen-transporting abilities, hemoglobin (Hb) is a protein of interest in the development of artificial oxygen therapeutics. Despite continuous formulation attempts, extracellular Hb solution often exhibits undesirable reactions when applied in vivo. Therefore, protein enginee...

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Detalles Bibliográficos
Autores principales: Kettisen, Karin, Dicko, Cedric, Smeds, Emanuel, Bülow, Leif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042259/
https://www.ncbi.nlm.nih.gov/pubmed/33859997
http://dx.doi.org/10.3389/fmolb.2021.649007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042259/
https://www.ncbi.nlm.nih.gov/pubmed/33859997
http://dx.doi.org/10.3389/fmolb.2021.649007

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