Increased Abundance of Nuclear HDAC4 Impairs Neuronal Development and Long-Term Memory

Dysregulation of the histone deacetylase HDAC4 is associated with both neurodevelopmental and neurodegenerative disorders, and a feature common to many of these disorders is impaired cognitive function. HDAC4 shuttles between the nucleus and cytoplasm in both vertebrates and invertebrates and altera...

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Detalles Bibliográficos
Autores principales: Main, Patrick, Tan, Wei Jun, Wheeler, David, Fitzsimons, Helen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042284/
https://www.ncbi.nlm.nih.gov/pubmed/33859551
http://dx.doi.org/10.3389/fnmol.2021.616642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042284/
https://www.ncbi.nlm.nih.gov/pubmed/33859551
http://dx.doi.org/10.3389/fnmol.2021.616642

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