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Increased Abundance of Nuclear HDAC4 Impairs Neuronal Development and Long-Term Memory
Dysregulation of the histone deacetylase HDAC4 is associated with both neurodevelopmental and neurodegenerative disorders, and a feature common to many of these disorders is impaired cognitive function. HDAC4 shuttles between the nucleus and cytoplasm in both vertebrates and invertebrates and altera...
Autores principales: | Main, Patrick, Tan, Wei Jun, Wheeler, David, Fitzsimons, Helen L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042284/ https://www.ncbi.nlm.nih.gov/pubmed/33859551 http://dx.doi.org/10.3389/fnmol.2021.616642 |
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