Mucoadhesive Microspheres of Maraviroc and Tenofovir Designed for Pre-Exposure Prophylaxis of HIV-1: An in vitro Assessment of the Effect on Vaginal Lactic Acid Bacteria Microflora

PURPOSE: To formulate and evaluate microspheres of the antiretroviral drugs maraviroc and tenofovir intended for a candidate vaginal microbicide and assess its effect on the vaginal lactic acid bacteria microflora. METHODS: Ionic gelation technique was used to formulate maraviroc and tenofovir micro...

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Detalles Bibliográficos
Autores principales: Ekama, Sabdat O, Ilomuanya, Margaret O, Azubuike, Chukwuemeka P, Bamidele, Tajudeen A, Fowora, Muinah A, Aina, Oluwagbemiga O, Ezechi, Oliver C, Igwilo, Cecilia I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042296/
https://www.ncbi.nlm.nih.gov/pubmed/33859500
http://dx.doi.org/10.2147/HIV.S291065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042296/
https://www.ncbi.nlm.nih.gov/pubmed/33859500
http://dx.doi.org/10.2147/HIV.S291065

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