Identification of the ternary complex of ribonuclease HI:RNA/DNA hybrid:metal ions by ESI mass spectrometry

Ribonuclease HI, an endoribonuclease, catalyzes the hydrolysis of the RNA strand of an RNA/DNA hybrid and requires divalent metal ions for its enzymatic activity. However, the mechanistic details of the activity of ribonuclease HI and its interaction with divalent metal ions remain unclear. In this...

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Detalles Bibliográficos
Autores principales: Ando, Tomoshige, Jongruja, Nujarin, Okumura, Nobuaki, Morikawa, Kosuke, Kanaya, Shigenori, Takao, Toshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042393/
https://www.ncbi.nlm.nih.gov/pubmed/33639158
http://dx.doi.org/10.1016/j.jbc.2021.100462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042393/
https://www.ncbi.nlm.nih.gov/pubmed/33639158
http://dx.doi.org/10.1016/j.jbc.2021.100462

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