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Rab8 attenuates Wnt signaling and is required for mesenchymal differentiation into adipocytes

Differentiation of mesenchymal stem cells into adipocyte requires coordination of external stimuli and depends upon the functionality of the primary cilium. The Rab8 small GTPases are regulators of intracellular transport of membrane-bound structural and signaling cargo. However, the physiological c...

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Detalles Bibliográficos
Autores principales: Stypulkowski, Ewa, Feng, Qiang, Joseph, Ivor, Farrell, Victoria, Flores, Juan, Yu, Shiyan, Sakamori, Ryotaro, Sun, Jiaxin, Bandyopadhyay, Sheila, Das, Soumyashree, Dobrowolski, Radek, Bonder, Edward M., Chen, Miao-Hsueh, Gao, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042397/
https://www.ncbi.nlm.nih.gov/pubmed/33662399
http://dx.doi.org/10.1016/j.jbc.2021.100488