Effective delivery of STING agonist using exosomes suppresses tumor growth and enhances antitumor immunity

The Stimulator of Interferon Genes (STING) pathway is implicated in the innate immune response and is important in both oncogenesis and cancer treatment. Specifically, activation of the cytosolic DNA sensor STING in antigen-presenting cells (APCs) induces a type I interferon response and cytokine pr...

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Detalles Bibliográficos
Autores principales: McAndrews, Kathleen M., Che, Sara P.Y., LeBleu, Valerie S., Kalluri, Raghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042450/
https://www.ncbi.nlm.nih.gov/pubmed/33711340
http://dx.doi.org/10.1016/j.jbc.2021.100523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042450/
https://www.ncbi.nlm.nih.gov/pubmed/33711340
http://dx.doi.org/10.1016/j.jbc.2021.100523

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