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Nucleolin acts as the receptor for C1QTNF4 and supports C1QTNF4-mediated innate immunity modulation

The C1q and TNF related 4 (C1QTNF4) protein is a structurally unique member of the C1QTNF family, a family of secreted proteins that have structural homology with both complement C1q and the tumor necrosis factor superfamily. C1QTNF4 has been linked to the autoimmune disease systemic lupus erythemat...

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Detalles Bibliográficos
Autores principales: Vester, Susan K., Beavil, Rebecca L., Lynham, Steven, Beavil, Andrew J., Cunninghame Graham, Deborah S., McDonnell, James M., Vyse, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042453/
https://www.ncbi.nlm.nih.gov/pubmed/33676896
http://dx.doi.org/10.1016/j.jbc.2021.100513