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The N2A region of titin has a unique structural configuration

The N2A segment of titin is a main signaling hub in the sarcomeric I-band that recruits various signaling factors and processing enzymes. It has also been proposed to play a role in force production through its Ca(2+)-regulated association with actin. However, the molecular basis by which N2A perfor...

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Detalles Bibliográficos
Autores principales: Stronczek, Chiara, Lange, Stephan, Bullard, Belinda, Wolniak, Sebastian, Börgeson, Emma, Mayans, Olga, Fleming, Jennifer R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042602/
https://www.ncbi.nlm.nih.gov/pubmed/33836065
http://dx.doi.org/10.1085/jgp.202012766