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The N2A region of titin has a unique structural configuration
The N2A segment of titin is a main signaling hub in the sarcomeric I-band that recruits various signaling factors and processing enzymes. It has also been proposed to play a role in force production through its Ca(2+)-regulated association with actin. However, the molecular basis by which N2A perfor...
Autores principales: | Stronczek, Chiara, Lange, Stephan, Bullard, Belinda, Wolniak, Sebastian, Börgeson, Emma, Mayans, Olga, Fleming, Jennifer R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042602/ https://www.ncbi.nlm.nih.gov/pubmed/33836065 http://dx.doi.org/10.1085/jgp.202012766 |
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