Cannabidiol inhibits the skeletal muscle Nav1.4 by blocking its pore and by altering membrane elasticity

Cannabidiol (CBD) is the primary nonpsychotropic phytocannabinoid found in Cannabis sativa, which has been proposed to be therapeutic against many conditions, including muscle spasms. Among its putative targets are voltage-gated sodium channels (Navs), which have been implicated in many conditions....

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Detalles Bibliográficos
Autores principales: Ghovanloo, Mohammad-Reza, Choudhury, Koushik, Bandaru, Tagore S., Fouda, Mohamed A., Rayani, Kaveh, Rusinova, Radda, Phaterpekar, Tejas, Nelkenbrecher, Karen, Watkins, Abeline R., Poburko, Damon, Thewalt, Jenifer, Andersen, Olaf S., Delemotte, Lucie, Goodchild, Samuel J., Ruben, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042605/
https://www.ncbi.nlm.nih.gov/pubmed/33836525
http://dx.doi.org/10.1085/jgp.202012701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042605/
https://www.ncbi.nlm.nih.gov/pubmed/33836525
http://dx.doi.org/10.1085/jgp.202012701

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