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Binary surrogate endpoints in clinical trials from the perspective of case definitions
INTRODUCTION: Surrogate endpoints are widely used in clinical trials, especially in situations where the endpoint of interest is not directly observable or to avoid long trial periods. A typical example for this case is frequently found in clinical trials in oncology, where overall survival (OS) as...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Akadémiai Kiadó
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042653/ https://www.ncbi.nlm.nih.gov/pubmed/33666567 http://dx.doi.org/10.1556/1886.2020.00031 |