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A cell-to-patient machine learning transfer approach uncovers novel basal-like breast cancer prognostic markers amongst alternative splice variants

BACKGROUND: Breast cancer is amongst the 10 first causes of death in women worldwide. Around 20% of patients are misdiagnosed leading to early metastasis, resistance to treatment and relapse. Many clinical and gene expression profiles have been successfully used to classify breast tumours into 5 maj...

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Detalles Bibliográficos
Autores principales: Villemin, Jean-Philippe, Lorenzi, Claudio, Cabrillac, Marie-Sarah, Oldfield, Andrew, Ritchie, William, Luco, Reini F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042689/
https://www.ncbi.nlm.nih.gov/pubmed/33845831
http://dx.doi.org/10.1186/s12915-021-01002-7