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A benchmark for RNA-seq deconvolution analysis under dynamic testing environments

BACKGROUND: Deconvolution analyses have been widely used to track compositional alterations of cell types in gene expression data. Although a large number of novel methods have been developed, due to a lack of understanding of the effects of modeling assumptions and tuning parameters, it is challeng...

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Detalles Bibliográficos
Autores principales: Jin, Haijing, Liu, Zhandong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042713/
https://www.ncbi.nlm.nih.gov/pubmed/33845875
http://dx.doi.org/10.1186/s13059-021-02290-6