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Evolution of Hominin Detoxification: Neanderthal and Modern Human Ah Receptor Respond Similarly to TCDD

In studies of hominin adaptations to fire use, the role of the aryl hydrocarbon receptor (AHR) in the evolution of detoxification has been highlighted, including statements that the modern human AHR confers a significantly better capacity to deal with toxic smoke components than the Neanderthal AHR....

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Detalles Bibliográficos
Autores principales: Aarts, Jac M M J G, Alink, Gerrit M, Franssen, Henk J, Roebroeks, Wil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042735/
https://www.ncbi.nlm.nih.gov/pubmed/33230523
http://dx.doi.org/10.1093/molbev/msaa287