Farnesoid X receptor via Notch1 directs asymmetric cell division of Sox9(+) cells to prevent the development of liver cancer in a mouse model

BACKGROUND: Asymmetrical cell division (ACD) maintains the proper number of stem cells to ensure self-renewal. The rate of symmetric division increases as more cancer stem cells (CSCs) become malignant; however, the signaling pathway network involved in CSC division remains elusive. FXR (Farnesoid X...

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Detalles Bibliográficos
Autores principales: Chen, Mi, Lu, Chenxia, Lu, Hanwen, Zhang, Junyi, Qin, Dan, Liu, Shenghui, Li, Xiaodong, Zhang, Lisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042944/
https://www.ncbi.nlm.nih.gov/pubmed/33845903
http://dx.doi.org/10.1186/s13287-021-02298-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042944/
https://www.ncbi.nlm.nih.gov/pubmed/33845903
http://dx.doi.org/10.1186/s13287-021-02298-6

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