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MSIFinder: a python package for detecting MSI status using random forest classifier

BACKGROUND: Microsatellite instability (MSI) is a common genomic alteration in colorectal cancer, endometrial carcinoma, and other solid tumors. MSI is characterized by a high degree of polymorphism in microsatellite lengths owing to the deficiency in the mismatch repair system. Based on the degree,...

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Detalles Bibliográficos
Autores principales: Zhou, Tao, Chen, Libin, Guo, Jing, Zhang, Mengmeng, Zhang, Yanrui, Cao, Shanbo, Lou, Feng, Wang, Haijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042960/
https://www.ncbi.nlm.nih.gov/pubmed/33845765
http://dx.doi.org/10.1186/s12859-021-03986-z