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Morphological and molecular characteristics of spheroid formation in HT-29 and Caco-2 colorectal cancer cell lines
BACKGROUND: Relapse and metastasis in colorectal cancer (CRC) are often attributed to cancer stem-like cells (CSCs), as small sub-population of tumor cells with ability of drug resistance. Accordingly, development of appropriate models to investigate CSCs biology and establishment of effective thera...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042991/ https://www.ncbi.nlm.nih.gov/pubmed/33849536 http://dx.doi.org/10.1186/s12935-021-01898-9 |