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Ligand Binding Prolongs Androgen Receptor Protein Half-Life by Reducing its Degradation

Androgens are important in female reproduction, but the molecular actions of androgens in female reproductive tissues are not fully understood. We investigated the androgen-responsive transcriptome in human and mouse granulosa cells (GCs) and surprisingly found that the gene-regulation activity of a...

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Detalles Bibliográficos
Autores principales: Astapova, Olga, Seger, Christina, Hammes, Stephen R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043068/
https://www.ncbi.nlm.nih.gov/pubmed/33869982
http://dx.doi.org/10.1210/jendso/bvab035