High-Oxygen Submersion Fetal Thymus Organ Cultures Enable FOXN1-Dependent and -Independent Support of T Lymphopoiesis

T cell development is effectively supported in fetal thymus organ cultures (FTOCs), which places thymus lobes atop an air-liquid interface (ALI) culture system. The direct exposure to air is critical for its success, as fetal thymus lobes placed in low oxygen submersion (LOS)-FTOCs fail to support t...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Jianxun, Zúñiga-Pflücker, Juan Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043069/
https://www.ncbi.nlm.nih.gov/pubmed/33859647
http://dx.doi.org/10.3389/fimmu.2021.652665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043069/
https://www.ncbi.nlm.nih.gov/pubmed/33859647
http://dx.doi.org/10.3389/fimmu.2021.652665

Ejemplares similares