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Selection of Optimal Bioinformatic Tools and Proper Reference for Reducing the Alignment Error in Targeted Sequencing Data
BACKGROUND: Careful design in the primary steps of a next-generation sequencing study is critical for obtaining successful results in downstream analysis. METHODS: In this study, a framework is proposed to evaluate and improve the sequence mapping in targeted regions of the reference genome. In this...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Wolters Kluwer - Medknow
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043119/ https://www.ncbi.nlm.nih.gov/pubmed/34026589 http://dx.doi.org/10.4103/jmss.JMSS_7_20 |