Selective Permeabilization of Gram-Negative Bacterial Membranes Using Multivalent Peptide Constructs for Antibiotic Sensitization

[Image: see text] The drug-impermeable bacterial membrane in Gram-negative pathogens limits antibiotic access to intracellular drug targets. To expand our rapidly waning antibiotic arsenal, one approach is to improve the intracellular delivery of drugs with historically poor accumulation in Gram-neg...

Descripción completa

Detalles Bibliográficos
Autores principales: Chan, Leslie W., Hern, Kelsey E., Ngambenjawong, Chayanon, Lee, Katie, Kwon, Ester J., Hung, Deborah T., Bhatia, Sangeeta N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043124/
https://www.ncbi.nlm.nih.gov/pubmed/33689277
http://dx.doi.org/10.1021/acsinfecdis.0c00805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8043124/
https://www.ncbi.nlm.nih.gov/pubmed/33689277
http://dx.doi.org/10.1021/acsinfecdis.0c00805

Ejemplares similares